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Monaldi Arch Chest Dis. 1997 Feb;52(1):24-6.

Bronchiolitis obliterans organizing pneumonia secondary to amiodarone: clinical, radiological and histological pattern.

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Division of Pneumology, Hospital of Vittorio Veneto, Italy.


The most common lung tissue reaction to amiodarone toxicity is a nonspecific pulmonary chronic interstitial pneumonia. In a minority of patients diffuse alveolar damage, alveolar haemorrhage or bronchiolitis obliterans organizing pneumonia (BOOP) is encountered. We report the case of a patient with clinical, functional, radiological and histological signs of BOOP secondary to amiodarone. The condition was partially reversible after suspending drug treatment, and resolved after corticosteroid treatment without relapse after a 14 month follow-up.

[Indexed for MEDLINE]

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