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Psychol Rep. 1996 Apr;78(2):391-400.

Environment is not the most important variable in determining oral morphine consumption in Wistar rats.

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Department of Psychology, New Mexico Tech, Socorro 87801, USA.


The role of differential housing on sucrose-morphine consumption in outbred Wistar rats was investigated in two studies. The results of earlier research, indicating rats housed in a quasinatural colony drank significantly less sucrose-morphine than rats isolated in standard laboratory cages, could not be replicated, as the consumption of sucrose-morphine by the isolated animals in the present two studies was reduced. It is possible that during a colony conversion the supplier inadvertently introduced strain differences making the present rats more resistant to xenobiotic consumption. Discussion documents the role of genetics in morphine consumption.

[Indexed for MEDLINE]

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