Format

Send to

Choose Destination
Urology. 1997 May;49(5A Suppl):108-10.

Hydroxyzine therapy for interstitial cystitis.

Author information

1
Department of Pharmacology / Experimental Therapeutics, Tufts University School of Medicine, New England Medical Center, Boston, Massachusetts 02111, USA.

Abstract

OBJECTIVES:

To determine the usefulness of oral hydroxyzine for the treatment of symptomatic interstitial cystitis.

METHODS:

This study was an open-label, nonconsecutive case series of patients treated by their local physicians, in consultation with the authors. A case-report form using visual analog scales was used to assess outcomes.

RESULTS:

Out of 140 patients, 90 (65%) returned the case-report forms. A 40% reduction in symptom scores was reported. This rose to 55% in patients with a history of allergies.

CONCLUSIONS:

Hydroxyzine is a useful drug for the symptomatic treatment of IC, especially in patients with documented allergies and/or evidence of bladder mast cell activation.

PMID:
9146011
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center