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Biol Pharm Bull. 1996 Apr;19(4):655-7.

Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis.

Author information

1
Research Institute for Wakan-Yaku (Traditional Sion-Japenese Medicines), Toyama Medicine and Pharmaceutical University, Japan.

Abstract

Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3,4-di-O-caffeoyl quinate (1) and 3,4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glycyrrhizin.

PMID:
9132180
[Indexed for MEDLINE]

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