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Intervirology. 1996;39(5-6):343-9.

The human cytomegalovirus major immediate-early gene.

Author information

1
Department of Microbiology and Immunology, Eastern Virginia Medical School, Norfolk 23501, USA.

Abstract

Immediate-early genes function to regulate viral and cellular gene expression during the course of virus replication. The major immediate-early gene region of human cytomegalovirus plays a key role in affecting activation and repression of viral and cellular genes. These proteins intimately associate and/or interact with viral and cellular proteins during this process. Herein, we will discuss the current understanding of this complex gene region.

PMID:
9130044
DOI:
10.1159/000150505
[Indexed for MEDLINE]

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