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Neurodegeneration. 1996 Dec;5(4):417-21.

Structural correlates of cognition in dementia: quantification and assessment of synapse change.

Author information

1
Department of Psychiatry, Western Psychiatric Institute & Clinic, Pittsburgh, PA 15261, USA. dekosky@vms.cis.pitt.edu

Abstract

Dementia results from a combination of structural and neurochemical pathologies. The most reliable index of cognition in both postmortem and biopsied AD brain is synapse loss.

PMID:
9117556
[Indexed for MEDLINE]

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