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Br J Dermatol. 1997 Mar;136(3):368-70.

Etretinate may work where acitretin fails.

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1
Department of Dermatology, Leicester Royal Infirmary, U.K.

Abstract

Acitretin (Ro 10-1670, Neotigason), a second-generation monoaromatic retinoid, is the main acid derivative and active metabolite of etretinate (Ro 10-9359, Tigason). Three patients who were unresponsive to treatment with acitretin but who responded to etretinate are reported. Twenty-nine patients in the U.K. are currently receiving etretinate on a named-patient basis. Possible explanations for the functional discrepancy between the two drugs are discussed.

PMID:
9115918
[Indexed for MEDLINE]
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