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Pathol Int. 1996 Dec;46(12):919-32.

Mouse mammary tumor virus and mammary tumorigenesis in wild mice.

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Nara Prefectural Institute of Public Health, Japan.


The current knowledge of the distribution of the mouse mammary tumor virus (MMTV) proviral genomes and the mechanism of mammary tumorigenesis by MMTV in mice, with the main emphasis on Asian feral mice, is reviewed. The relevant earlier discoveries on the mode of MMTV transmission are summarized to provide an outline of the biology of MMTV. Finally, the viral etiology of human breast cancer will be discussed.

[Indexed for MEDLINE]

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