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Trends Microbiol. 1997 Feb;5(2):74-82.

Leukemogenesis by Moloney murine leukemia virus: a multistep process.

Author information

1
Dept of Molecular Biology, University of California, Irvine 92717, USA. hyfan@uci.edu

Abstract

Moloney murine leukemia virus is a prototypical simple retrovirus that has been an extremely useful model for leukemogenesis. Important steps in leukemogenesis include proviral activation of cellular proto-oncogenes, generation of mink cell focus-inducing recombinants, and early (preleukemic) virus-induced changes in hematopoiesis.

PMID:
9108934
DOI:
10.1016/S0966-842X(96)10076-7
[Indexed for MEDLINE]

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