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Neuroradiology. 1997 Mar;39(3):171-4.

Atypical MRI features of Wilson's disease: high signal in globus pallidus on T1-weighted images.

Author information

1
Third Department of Internal Medicine, National Defense Medical College, Saitama, Japan.

Abstract

Most reports of MRI in Wilson's disease have been of abnormal low-signal lesions on T1-weighted images and high signal intensity on T2-weighted images. In contrast, we report three patients who had high-signal lesions in the globus pallidus on T1-weighted images, a finding seen in patients with portal-systemic encephalopathy. The possible causes include the paramagnetic effect of copper or iron and accumulation of Alzheimer type II glial cells.

PMID:
9106287
DOI:
10.1007/s002340050386
[Indexed for MEDLINE]

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