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JAMA. 1997 Apr 16;277(15):1214-8.

Chlamydia pneumoniae as a new source of infectious outbreaks in nursing homes.

Author information

1
Ontario Ministry of Health, Toronto, Canada.

Erratum in

  • JAMA 1997 Jul 9;278(2):118.

Abstract

OBJECTIVE:

To determine the extent and severity of illness and mode of transmission of Chlamydia pneumoniae infection in 3 nursing home outbreaks.

DESIGN AND SETTING:

Retrospective cohort study in 3 nursing homes in Ontario from September to November 1994.

SUBJECTS:

A total of 549 residents and 65 staff members.

MAIN OUTCOME MEASURES:

Morbidity and mortality were determined by a review of disease surveillance forms, residents' charts, and a self-administered questionnaire to staff. Single and paired serum samples for C pneumoniae serological testing and nasopharyngeal swabs for C pneumoniae culture were collected, and direct fluorescent antibody assays were performed to confirm C pneumoniae infection.

RESULTS:

The attack rates for confirmed and suspected cases combined were 68%, 46%, and 44% among residents in nursing homes A, B, and C, respectively, and 34% among nursing home C staff. A total of 16 cases of pneumonia confirmed by chest x-ray and 6 deaths were identified. The spectrum of illness among nursing home C residents included a new cough in 58 (100%), fever in 37 (64%), sore throat in 14 (24%), and hoarseness in 8 (14%). Staff members at nursing home C were more likely to report hoarseness (P<.001) and sore throat (P<.001). Residents who smoked had onset of illness earlier than nonsmokers (P=.007), which perhaps is related to airborne transmission in a designated smoking room.

CONCLUSIONS:

Chlamydia pneumoniae caused serious morbidity and mortality among residents and morbidity among staff; C pneumoniae is an important cause of respiratory disease outbreaks in nursing homes, and diagnostic tests must be readily available for early recognition of C pneumoniae infections.

PMID:
9103345
[Indexed for MEDLINE]

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