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Curr Opin Immunol. 1997 Apr;9(2):177-82.

Single cell analyses of cytokine production.

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  • 1Trudeau Institute, New York, NY 12983, USA.


Subsets of T lymphocytes have been defined by their secretion of polarized patterns of cytokines. Type 1 and Type 2 subsets have been characterized in a variety of model systems both in vivo and in vitro and are a useful framework for studying immune responses. Recent technical advances have made it possible to analyze cytokine production by these populations at the level of individual cells.

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