Format

Send to

Choose Destination
Curr Opin Immunol. 1997 Apr;9(2):183-8.

Advances in gene targeting methods.

Author information

1
Institute for Genetics, Department for Immunology, Cologne, Germany. rkuehn@gen1.genetik.uni-koeln.de

Abstract

Gene targeting in embryonic stem cells is commonly used for gene inactivation and the generation of mouse mutants. The combined use of methods for site-specific and homologous DNA recombination expands the potential of gene targeting in embryonic stem cells considerably and offers the opportunity of conditional gene targeting in mice.

PMID:
9099792
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science Icon for MDC Library - SFX Icon for Max Delbrueck Center for Molecular Medicine, MDC Library, Berlin, Germany
Loading ...
Support Center