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J Physiol Paris. 1996;90(5-6):361-6.

Plasticity of the hippocampal-prefrontal cortex synapses.

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Laboratoire de Neurobiologie de l'Apprentissage et de la Mémoire, CNRS-URA 1491, Université Paris Sud, Orsay, France.


This paper summarizes experiments showing that the direct excitatory glutamergic pathway projecting from area CA1 and subiculum to the prefrontal cortex in the rat express a long-lasting NMDA receptor-dependent form of LTP that can be induced for several days in the freely-moving rat. Other experiments examined its functional significance in learning and the role of dopamine in the regulation of hippocampal-prefrontal cortex plasticity.

[Indexed for MEDLINE]

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