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J Mol Evol. 1997 Apr;44(4):371-7.

Complete sequence of SpHox8 and its linkage in the single Hox gene cluster of Strongylocentrotus purpuratus.

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Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.


SpHox8 is the paralog group 8 Hox gene of Strongylocentrotus purpuratus. This identification follows from an analysis of the sequence of the complete open reading frame of a late-gastrula-stage cDNA clone; from direct linkage to adjacent Hox genes in a fosmid contig; and from blot hybridizations carried out on pulse field gel electrophoretic separations. SpHox8 is a single-copy gene, and there is only one Hox gene cluster per genome in S. purpuratus.

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