Format

Send to

Choose Destination
J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):147-52.

Pattern of brain morphology in patients with schizophrenia and large cavum septi pellucidi.

Author information

1
University of Iowa Hospitals and Clinics, Mental Health Clinical Research Center, Iowa City, IA 52242, USA.

Abstract

Cavum septi pellucidi (CSP) is a midline developmental anomaly shown to have increased incidence in patients with schizophrenia. The etiology of CSP may involve dysgenesis of the temporal lobes. This study evaluated the pattern of brain changes in three groups: 1) normal control subjects, 2) schizophrenic subjects without large CSP, and 3) schizophrenic subjects with large CSP. Patients without large CSP had decreased total brain, frontal, and temporal lobe volumes; patients with the anomaly had more pronounced right > left asymmetry and volume decrement limited to the left temporal lobe. These findings indicate that patients with schizophrenia and large CSP may show a different pattern of disturbed brain morphology than patients without this abnormality.

PMID:
9081549
DOI:
10.1176/jnp.8.2.147
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center