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Phys Med Biol. 1997 Mar;42(3):583-93.

Uniform irradiation of irregularly shaped cavities for photodynamic therapy.

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Laser Centre, Academic Medical Centre, Amsterdam, The Netherlands.


It is difficult to achieve a uniform light distribution in irregularly shaped cavities. We have conducted a study on the use of hollow 'integrating' moulds for more uniform light delivery of photodynamic therapy in irregularly shaped cavities such as the oral cavity. Simple geometries such as a cubical box, a sphere, a cylinder and a 'bottle-neck' geometry have been investigated experimentally and the results have been compared with computed light distributions obtained using the 'radiosity method'. A high reflection coefficient of the mould and the best uniform direct irradiance possible on the inside of the mould were found to be important determinants for achieving a uniform light distribution.

[Indexed for MEDLINE]

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