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Annu Rev Physiol. 1997;59:413-36.

Renal K+ channels: structure and function.

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Department of Pharmacology, New York Medical College, Valhalla 10595, USA.


The activity of potassium (K+) channels is intimately linked to several important transport functions in renal tubules. We review recent progress concerning the properties, site along the nephron, and physiological regulation of native K+ channels, and compare their characteristics with those of recently cloned K+ channels. We do not fully cover work on K+ channels in amphibian tubules, cell cultures, and single tubule cells and do not review K+ channels in mesangial cells.

[Indexed for MEDLINE]

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