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Annu Rev Physiol. 1997;59:1-21.

Lung surfactant: a personal perspective.

Author information

1
Cardiovascular Research Institute, University of California, San Francisco 94143-0130, USA.

Abstract

This perspective tells the story of the discovery, characterization, and understanding of the surfactant system of the lung; of how investigators from many disciplines studied the system, stimulated by the demonstration of surfactant deficiency in respiratory distress syndrome of the newborn; and of how the resulting knowledge formed a basis for highly successful surfactant substitution treatment for this syndrome. The chapter includes personal reminiscences and reflections of the author and ends with a few thoughts about the present status and future prospects of this field of research.

PMID:
9074754
DOI:
10.1146/annurev.physiol.59.1.1
[Indexed for MEDLINE]

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