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Curr Biol. 1997 Jan 1;7(1):R24-7.

Genetic recombination: sex-change operations in yeast.

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1
Department of Molecular Biology, University of Geneva, 30 quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland. David.Shore@molbio.unige.ch

Abstract

The 'directionality' of mating-type switching in building yeast is determined by mechanisms that regulate genetic recombination along the whole left arm of chromosome III. In MATa cells, a cis-acting 'recombinational enhancer' activates this entire region, while in MATalpha cells the enhancer is turned off by the alpha2 repressor.

PMID:
9072164
[Indexed for MEDLINE]
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