Format

Send to

Choose Destination
Curr Opin Cell Biol. 1997 Apr;9(2):205-12.

T cell antigen receptor signal transduction.

Author information

1
Howard Hughes Medical Institute, Department of Medicine, U426, University of California, San Francisco, CA 94143, USA. qian@cgl.ucsf.edu

Abstract

The T cell antigen receptor (TCR) initiates signal transduction by activating multiple cytoplasmic protein tyrosine kinases (PTKs). Considerable progress in the field of TCR signal transduction has been made in three areas recently: first, in understanding the structure and function of the PTK ZAP-70; second, in the elucidation of the function of the substrates and pathways downstream of the PTKs; and third, in the identification of molecules that negatively regulate TCR signalling.

PMID:
9069257
DOI:
10.1016/s0955-0674(97)80064-6
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center