Format

Send to

Choose Destination
Am J Ophthalmol. 1997 Mar;123(3):303-12.

Amniotic membrane transplantation for persistent epithelial defects with ulceration.

Author information

1
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida.

Abstract

PURPOSE:

To determine whether preserved human amniotic membrane can be used as an alternative substrate for treating persistent corneal epithelial defects with sterile ulceration.

METHODS:

Amniotic membrane transplantation was performed in 11 eyes of 11 consecutive patients with corneal ulcers of different causes that had persisted for a mean +/- SD of 17.5 +/- 13.9 weeks.

RESULTS:

Ten patients healed in 3.9 +/- 2.3 weeks (P < .01) without recurrence for 9.0 +/- 5.9 months. One patient failed to heal because of preexisting corneal perforation pursuant to severe rheumatoid arthritis.

CONCLUSION:

Amniotic membrane transplantation may be considered an alternative method for treating persistent epithelial defects and sterile ulceration that are refractory to conventional treatment and before considering treatment by conjunctival flaps or tarsorrhaphy.

PMID:
9063239
DOI:
10.1016/s0002-9394(14)70125-4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center