Send to

Choose Destination
Immunol Rev. 1997 Feb;155:145-54.

Arousal and inhibition of human NK cells.

Author information

DNAX Research Institute of Molecular and Cellular Biology, Department of Human Immunology, Palo Alto, CA 94304, USA.


NK cells express receptors for polymorphic MHC class I molecules that inhibit killing of potential target cells bearing appropriate class I allotypes. Here we review the membrane receptors on human NK cells that are known to initiate cell-mediated cytotoxicity and demonstrate regulation of these responses by the killer cell inhibitory (KIR) receptors.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center