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Postgrad Med. 1997 Feb;101(2):181-2, 185-7.

Gastroesophageal reflux disease: gaining control over heartburn.

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McGraw-Hill Healthcare Information Group, Minneapolis, MN 55435, USA.


GERD is a common disorder. Symptoms of reflux, such as heartburn, are due to a combination of factors: relaxation of the lower esophageal sphincter, hypersecretion of gastric acid, and resulting burning of the esophageal mucosa. Symptoms are usually classified as classic, atypical, or complicated. Treatment approaches include dietary and lifestyle changes, reduction of acidity with use of H2 receptor antagonists, and reduction of acid secretion with use of proton pump inhibitors. Patient motivation is an important factor in the management of gastroesophageal reflux. In rare instances, patients do not respond to medical treatment and are candidates for antireflux surgery.

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