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Arch Surg. 1997 Feb;132(2):209-10.

Interleukin-6 and a delay of neutrophil apoptosis after major surgery.

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Department of Clinical Pharmacology, Jichi Medical School, Tochigi, Japan.


Surgical treatments affect host immune systems. Apoptosis of the circulatory lymphocytes and an elevation of the number of neutrophils are induced by surgery. These alterations are not dependent only on the stress hormone. The course of neutrophilia and the serum concentration of interleukin-6 are given after various surgical treatments. Neutrophil-mediated lung injury is discussed.

[Indexed for MEDLINE]

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