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J Am Vet Med Assoc. 1997 Feb 15;210(4):519-24.

Seroprevalence of antibodies to Sarcocystis neurona in horses residing in Ohio.

Author information

1
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University Columbus 43210, USA.

Abstract

OBJECTIVE:

To determine the seroprevalence of serum antibodies to Sarcocystis neurona in horses residing in Ohio.

DESIGN:

Prevalence survey.

SAMPLE POPULATION:

Serum from samples from 1,056 horses. Serum was collected on every 36th sample submitted to the Ohio State Diagnostic Laboratory for testing for equine infectious anemia.

PROCEDURE:

Serum was frozen at -80 C and analyzed for antibodies to S neurona, using a western blot. Information regarding blood sample collection, age, breed, sex, and geographic location was recorded for each horse. Data were analyzed, using multivariable logistic regression.

RESULTS:

Horses of 37 breeds from 81 of Ohio's 88 counties were included in the study population. There were 481 females, 133 males, and 442 geldings ranging in age from 3 months to 27 years; > 48% were < 5.6 years old. More than 53% of samples were seropositive for antibodies to S neurona. A gender or breed effect on seroprevalence was not identified. There was a significant effect of age (P < or = 0.0001; with older horses more likely to be affected), and of location (statistical and extension districts; P = 0.02 and P = 0.03, respectively) on seroprevalence. Location effects appeared to be correlated to the number of days with temperatures below freezing (P < 0.05).

CLINICAL IMPLICATIONS:

The high seroprevalence of antibodies to S neurona found in the sample population emphasizes the importance of examining CSF for S neurona-specific antibodies when establishing a diagnosis of equn protozoal myeloencephalitis.

PMID:
9040839
[Indexed for MEDLINE]

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