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Curr Opin Immunol. 1997 Feb;9(1):10-6.

Origin, maturation and antigen presenting function of dendritic cells.

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Basel Institute for Immunology, Grenzacherstrasse 487, CH4005 Basel, Switzerland.


Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.

[Indexed for MEDLINE]

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