Format

Send to

Choose Destination
Curr Opin Immunol. 1997 Feb;9(1):44-51.

Role of natural killer cells in innate resistance to protozoan infections.

Author information

1
Immunobiology Section, Laboratory of Parasitic Diseases, National Institute for Allergy and Infectious Diseases, 9000 Rockville Pike, Building 4, Room 126, Bethesda, MD 20892-0425, USA. Tkersten@atlas.niaid.nih.gov

Abstract

Natural killer cells are now recognized as major effectors of innate resistance to protozoan parasites. The principal mechanism by which they control the growth of these pathogens is indirect, involving cytokine production rather than cytolytic activity. Recent studies have identified a series of positive and negative signals provided by cytokines and cellular interactions which regulate protozoa-induced natural killer cell function.

PMID:
9039777
DOI:
10.1016/s0952-7915(97)80157-4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center