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Rheum Dis Clin North Am. 1997 Feb;23(1):119-32.

Obstetric management of the high-risk lupus pregnancy.

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Harvard Medical School, Massachusetts General Hospital, Boston, USA.


With improvements in diagnosis and treatment, the prognosis of patients with systemic lupus erythematosus has generally improved in recent years, and similarly the outlook for women who become pregnant in the setting of this disorder is far more optimistic than it once was. The risk of significant morbidity to both the mother and fetus exists, however. Beginning with preconception counseling, a careful and thorough approach to the care of the patient and cooperation among her various health care providers optimizes the chance of a successful pregnancy.

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