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Klin Oczna. 1996 Feb;98(2):101-4.

[Serotonin in diabetic retinopathy].

[Article in Polish]

Author information

1
Kliniki Okulistycznej AM w BiaƂymstoku.

Abstract

PURPOSE:

The present study was designed to evaluate a possible participation of serotonin in the development of retinopathy in diabetes mellitus.

MATERIAL AND METHODS:

Serotonin of whole blood and platelets was studied in 12 patients with Type I and II diabetes using high pressure liquid chromatography method.

RESULTS:

The concentration of serotonin in the blood was markedly increased (210 +/- 50 ng/ml in diabetes and 150 +/- 35 ng/ml in control, p < 0.01) and not changed in platelets in diabetes. There was a relation between blood serotonin level and the presence of retinopathy.

CONCLUSION:

These results suggest that serotonin may be involved in the pathogenesis of diabetic microangiopathy.

PMID:
9026563
[Indexed for MEDLINE]

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