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Cytokine Growth Factor Rev. 1996 Dec;7(4):311-25.

Functions of fibroblast growth factors in vertebrate development.

Author information

1
Brookdale Center for Molecular Biology, Mount Sinai School of Medicine, New York, NY 10029, USA. mgoldfa@smtplink.mssm.edu

Abstract

Fibroblast growth factors (FGFs) are a class of secreted polypeptide ligands which mediate diverse cellular responses during embryonic, fetal, and postnatal vertebrate development. The purposes of this review are to provide a condensed overview of FGFs and their receptors, to catalog and categorize the functions of FGFs in vertebrate development, to present recent discoveries relating to the interplay of FGFs with other secreted ligands in the control of tissue growth and patterning, and to discuss several potential directions for future research in the field.

PMID:
9023055
DOI:
10.1016/s1359-6101(96)00039-1
[Indexed for MEDLINE]

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