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Nihon Rinsho. 1997 Jan;55(1):222-6.

[18F-fluorodeoxyglucose positron emission tomography in Parkinson's disease].

[Article in Japanese]

Author information

  • 1Department of Neurology, Nagoya University School of Medicine.

Abstract

Positron emission topographic studies on local cerebral glucose metabolism in Parkinson's disease (PD) including our own data were reviewed. In our 18F-FDG PET studies, local or global metabolic change was not found in 9 patients with non-demented PD, with respect to 5 normal controls. Moreover, there was not an apparent difference between severe PD group (Hoehn-Yahr III-IV) and mild PD group (Hoehn-Yahr I-II). In other PD patients with dementia or autonomic failure, parietal dominant hypometabolism was found likely to those of Alzheimer disease, but lenticular nucleus was well preserved. Furthermore 18F-FDG PET findings of atypical parkinsonian syndromes, such as SND and PSP were reviewed. They showed relative hypometabolism in the basal ganglia in PET images. PET study with FDG provides a clue to differential diagnosis of parkinsonian patients.

PMID:
9014454
[PubMed - indexed for MEDLINE]
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