Format

Send to

Choose Destination
Curr Opin Cell Biol. 1997 Feb;9(1):70-5.

ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction.

Author information

1
Department of Cell Biology, Faculty of Medicine, Kyoto University, Yoshida-Konoe, Sakyo-ku, Kyoto 606, Japan.

Abstract

The ERM family consists of three closely related proteins, ezrin, radixin, and moesin, that are thought to work as cross-linkers between plasma membranes and actin-based cytoskeletons. Recent analyses of the structure and functions of ERM proteins have revealed that these molecules are involved not only in cytoskeletal organization but also in signal transduction. Furthermore, identification of the neurofibromatosis type 2 tumour suppressor, which shows striking sequence similarity to ERM proteins, has increased interest in this family.

PMID:
9013673
DOI:
10.1016/s0955-0674(97)80154-8
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center