Send to

Choose Destination
Curr Opin Cell Biol. 1997 Feb;9(1):54-61.

Actin dynamics in vivo.

Author information

Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143-0450, USA.


Actin dynamics in lamellipodia are driven by continuous cycles of actin polymerization, retrograde flow, and depolymerization. In the past year, advances have been made in identifying signaling pathways that regulate actin-filament uncapping and polymerization, in determining the role of myosin motor proteins in retrograde flow, and in evaluating the role of severing proteins in actin depolymerization. Both Listeria monocytogenes and Saccharomyces cerevisiae have emerged as powerful model organisms for studying actin dynamics in cells.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center