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Life Sci. 1997;60(4-5):245-51.

Adenosine and neuronal plasticity.

Author information

1
Laboratory of Pharmacology, Gulbenkian Institute of Science, Oeiras, Portugal.

Abstract

Adenosine is considered an important neuromodulator of the nervous system acting at pre-, post- and non-synaptic levels. In the present review we describe how adenosine modifies paired-pulse facilitation (PPF), posttetanic depression (PTD), long-term potentiation (LTP), long-term depression (LTD) and depotentiation at the hippocampus, and therefore how this nucleoside modulates synaptic plasticity.

PMID:
9010479
DOI:
10.1016/s0024-3205(96)00544-9
[Indexed for MEDLINE]

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