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J Protein Chem. 1996 Nov;15(8):721-9.

A vector projection method for predicting supersecondary motifs.

Author information

1
Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China.

Abstract

For the 11 types of most frequently occurring supersecondary motifs, we used a new method--the vector projection method--to predict a protein's supersecondary structure. In a training set of peptides and a test set of peptides we obtained a satisfactory result, with a prediction accuracy of about 90%. The high prediction accuracy indicates that this method is reasonable for predicting the folding motifs of proteins. This work provides insight into the problem of predicting a protein's local structure accurately, and is of particular value in protein modeling, prediction, and molecule design.

PMID:
9008295
[Indexed for MEDLINE]

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