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Curr Opin Immunol. 1996 Dec;8(6):872-7.

Cytokines in autoimmunity.

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Kennedy Institute of Rheumatology, Hammersmith, London, UK.


The past few years have witnessed exciting developments regarding the role of cytokines in autoimmune diseases, particularly in rheumatoid arthritis and Crohn's disease, with the demonstration that anti-TNF alpha therapy is clinically beneficial and provides reproducible results. Recent contributions to this field, derived from in vivo studies in animal models of autoimmunity, and increasingly from clinical trials, have greatly enhanced our understanding of this field.

[Indexed for MEDLINE]

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