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Curr Opin Immunol. 1996 Dec;8(6):808-14.

T cell selection and autoimmunity: flexibility and tuning.

Author information

1
Department of Medical Biophysics, Ontario Cancer Institute, Toronto, Canada. pohashi@oci.utoronto.ca

Abstract

Peptide-MHC interactions govern the fate of T cells in the thymus and the peripheral T cell repertoire. Recent progress has involved investigating how different peptides influence T cell selection and mature T cell function and the subsequent implications for tolerance and autoimmunity.

PMID:
8994860
DOI:
10.1016/s0952-7915(96)80009-4
[Indexed for MEDLINE]

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