Fab' fragments of a mAb to a member of family 2 of trans-sialidases of Trypanosoma cruzi block trypanosome invasion of host cells and neutralize infection by passive immunization

Ann N Y Acad Sci. 1996 Oct 25:797:242-5. doi: 10.1111/j.1749-6632.1996.tb52965.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / immunology
  • Antibodies, Protozoan / immunology
  • Antigens, Protozoan / immunology
  • Chagas Disease / immunology*
  • Glycoproteins / immunology*
  • Heart / parasitology
  • Immunization, Passive*
  • Immunoglobulin Fab Fragments / immunology*
  • Mice
  • Mice, Inbred BALB C
  • Neuraminidase / immunology*
  • Trypanosoma cruzi / enzymology
  • Trypanosoma cruzi / immunology*
  • Trypanosoma cruzi / pathogenicity

Substances

  • Antibodies, Monoclonal
  • Antibodies, Protozoan
  • Antigens, Protozoan
  • Glycoproteins
  • Immunoglobulin Fab Fragments
  • trans-sialidase
  • Neuraminidase