Format

Send to

Choose Destination
Experientia. 1996 Dec 15;52(12):1021-5.

Molecular machinery mediating vesicle budding, docking and fusion.

Author information

1
Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

Abstract

A general machinery buds and fuses transport vesicles which connect intracellular compartments with each other and allow communication with the extracellular environment. Cytoplasmic coat proteins deform membranes to bud vesicles and interact directly or indirectly with cargo molecules. Compartment-specific SNAREs (SNAP receptors) on vesicles and target membranes dock vesicles and provide a scaffolding for the general fusion machinery to initiate lipid bilayer fusion.

PMID:
8988241
DOI:
10.1007/bf01952097
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center