Send to

Choose Destination
Bioseparation. 1996 Feb;6(1):1-15.

Glycoproteins: a consideration of the potential problems and their solutions with respect to purification and characterisation.

Author information

Research Laboratory for the Chemistry Bioactive Carbohydrates and Proteins, School of Chemistry, University of Birmingham, UK.


Glycoproteins, as a class of biomolecules, present a number of differences in structure and function from non-glycosylated proteins. This makes their purification and characterisation a potentially daunting prospect. This article provides a brief summary of the occurrence, structure and composition of glycoproteins and the main areas where these factors may complicate the purification and characterisation process. There follows a review of the range of techniques available, an insight into the choices of ways forward in considering glycoprotein purification and characterisation. Appropriate prominence is given to lectins; their application to the purification, identification and characterisation of glycoproteins, and the major contribution they have made to the study of this class of biomolecules.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center