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Am J Chin Med. 1996;24(3-4):263-9.

Investigation of the anti-inflammatory activity of Acacia nilotica and Hibiscus sabdariffa.

Author information

1
Department of Biochemistry, College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia.

Abstract

The aqueous extracts of Acacia nilotica and Hibiscus sabdariffa were tested for anti-inflammatory, analgesic and antipyretic activities in animal models. Acacia nilotica extract had an inhibitory effect on carrageenan induced paw edema and yeast-induced pyrexia in rats. It also produced a significant increase in the hot plate reaction time in mice. Hibiscus sabdariffa extract had no effect on paw edema but had an inhibitory effect on yeast induced pyrexia and a significant effect on the hot plate reaction time. Among the phytoconstituents found in both plants, flavanoids, polysaccharides and organic acids may be mainly responsible for their pharmacological activities.

PMID:
8982438
DOI:
10.1142/S0192415X96000323
[Indexed for MEDLINE]

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