Send to

Choose Destination
J Am Vet Med Assoc. 1997 Jan 1;210(1):51-4.

Malignant hyperthermia-like reaction secondary to ingestion of hops in five dogs.

Author information

National Animal Poison Control Center (presently the ASPCA National Animal Poison Control Center), College of Veterinary Medicine, University of Illinois, Urbana 61801, USA.


Five dogs, 4 of which were Greyhounds, suffered adverse effects secondary to the ingestion of spent hops. Mean time to onset of clinical signs was 3 hours, and clinical signs included marked hyperthermia, restlessness, panting, vomiting, signs of abdominal pain, and seizures. Four of the 5 dogs died despite aggressive therapeutic measures, and there was rapid onset of rigor mortis in 3. The overrepresentation of Greyhounds, coupled with the clinical signs, was suggestive of a malignant hyperthermia-like response to the ingestion of hops. It also is possible that hops contain an uncoupler of oxidative phosphorylation.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center