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Respiration. 1996;63(2):84-7.

Asthmatic reactions after nasal allergen provocation.

Author information

1
Medical Department, Ruhr University of Bochum, Germany.

Abstract

Three bronchoconstrictive responses associated with acute rhinitis and occurring in two patients were observed among 400 nasal allergen challenges. Causative substances were birch pollen, Dermatophagoides pteronyssinus and HSA-conjugated pyromellitic dianhydride. Both subjects showed bronchial hyperreactivity and immediate-type sensitization to these allergens. It is concluded that bronchoobstruction nearly occurs in nasal allergen challenges. The underline pathophysiological mechanism remains unclear.

PMID:
8966371
DOI:
10.1159/000196523
[Indexed for MEDLINE]

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