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Gene. 1996 Sep 16;173(2):261-4.

Cloning and sequence analysis of the human salivary peroxidase-encoding cDNA.

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  • 1Department of Pediatric Dentistry, University of Alabama Schools of Medicine and Dentistry, Birmingham, AL 35294, USA.


A cDNA (hSPO) encoding human salivary peroxidase (hSPO) was isolated and its nucleotide (nt) sequence determined. The coding sequence resembles those of other mammalian peroxidases and contains a 3' untranslated region of 538 nt. In a rabbit reticulocyte lysate transcription/translation system, the cDNA produces a major protein of approx. 67 kDa, which corresponds to the calculated molecular weight of unglycosylated hSPO.

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