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C R Seances Soc Biol Fil. 1996;190(4):497-501.

[Induction of prostatic buds in the urogenital sinus in Tfm mouse embyos without androgen receptors].

[Article in French]

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1
Département de Biologie, Faculté des Sciences pharmaceutiques, Teikyo Université, Kanagawa-ken, Japan.

Abstract

We have studied the prostatic bud induction in the urogenital sinus of androgen-receptor deficient mice, and found that epidermal growth factor (EGF), keratinocyte growth factor (KGF) as well as transforming growth factor-alpha (TGF-alpha) can provoke prostatic bud formation in the androgen-receptor deficient sinus cultured in the medium deprived of androgens.

PMID:
8952900
[Indexed for MEDLINE]
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