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Eur J Clin Microbiol Infect Dis. 1996 Oct;15(10):820-3.

Meningitis due to enterotoxigenic Bacteroides fragilis.

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Laboratoire de Microbiologie A, Centre Hospitalier Universitaire La Milètrie, Poitiers, France.


An enterotoxigenic strain of Bacteroides fragilis was the sole organism isolated from the cerebrospinal fluid of a two-and-a-half-month neonate who had a medullary-colonic fistula as part of a complex congenital malformation, but no brain abscess. A rapid latex particle agglutination test for detection of bacterial antigen was positive for Haemophilus influenzae type b, suggesting that Bacteroides fragilis and Haemophilus influenzae type b might share some capsular antigens. In order to determine the role of the enterotoxin with respect to virulence of the strain, antibodies to a 20 kDa protein were sought in the patient's serum, but Western blot of the culture supernatant revealed only antibodies to a 45 kDa bacterial protein. The patient was successfully treated with metronidazole and imipenem.

[Indexed for MEDLINE]

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