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Brain Res Dev Brain Res. 1996 Nov 22;97(1):148-51.

Postnatal development of peripheral-type benzodiazepine receptors in rat brain and peripheral tissues.

Author information

1
Department of Neuropsychiatry, Tokyo Medical and Dental University School of Medicine, Japan.

Abstract

We examined the postnatal development of peripheral-type benzodiazepine receptors (PBRs), labelled with [3H]PK 11195, in rat brain and peripheral tissues. Specific [3H]PK 11195 binding exhibited a heterogeneous patterns of postnatal development in the rat: three patterns of increase, decrease and no change. Hence, the density of the PBRs can be independently regulated in each tissue during postnatal development, and the postnatal alterations in the density might be parallel with the functional activities coupled to the receptors.

PMID:
8946064
[Indexed for MEDLINE]

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