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Chem Biol. 1996 Nov;3(11):895-904.

Matrix metalloproteinases and the development of cancer.

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  • 1Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143-0534, USA.

Abstract

Proteolytic remodeling of the extracellular matrix is an important aspect of the creation and progression of cancer. Matrix metalloproteinases are important at several points during multi-stage neoplastic progression in tumor cells and responding blood vessels, inflammatory cells and stroma.

PMID:
8939708
[PubMed - indexed for MEDLINE]
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