Format

Send to

Choose Destination
Curr Biol. 1996 Oct 1;6(10):1241-3.

Apoptosis: telling cells their time is up.

Author information

1
Department of Genetics, Osaka University Medical School, Japan.

Abstract

Ligand engagement by the receptor Fas leads to apoptosis. A clue to how this happens comes from the discovery that ligand binding leads to recruitment to Fas of a protease, homologous to interleukin-1 beta converting enzyme, likely to initiate a proteolytic cascade that drives apoptosis.

PMID:
8939562
DOI:
10.1016/s0960-9822(02)70706-9
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center